![]() ![]() Several host factors with antiviral potential are now implicated in the regulation of virus entry, including cholesterol 25-hydroxylase (CH25H), lymphocyte antigen 6E (LY6E), nuclear receptor co-activator protein 7 (NCOA7), interferon-γ-inducible lysosomal thiol reductase (GILT), CD74 and ARFGAP with dual pleckstrin homology domain-containing protein 2 (ADAP2). However, the progressive development of genetic and pharmacological screening platforms and the onset of the COVID-19 pandemic have galvanized interest in how viruses infiltrate cells and how cells defend against it. The interferon-induced transmembrane (IFITM) proteins, known for inhibiting fusion between viral and cellular membranes, were once the only factors known to restrict virus entry. However, while the prevention of virus invasion by humoral immunity is well appreciated, considerably less is known about the immune defences present within cells (known as intrinsic immunity) that interfere with virus entry. Most antiviral vaccines induce neutralizing antibodies that prevent virus entry into cells. Virus entry, consisting of attachment to and penetration into the host target cell, is the first step of the virus life cycle and is a critical ‘do or die’ event that governs virus emergence in host populations. ![]()
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![]() Handbrake is a powerful, free, and open source video transcoder that is available for Windows, Linux, and Max. Here is a rich list of such go-to video transcoder programs. In addition to the core function, these video converter tools also deliver extra nifty features like video editing, video downloading, and see faster development and customization compared to closed source software. For instance, the Apple MOV video format can be converted to a more universal MP4 or MP3 format to ensure that anyone can open it without the need for any pricey and bulky specialized software. ![]() The best open source video converter comes in handy to sail you to a reliable and convenient media consumption experience all for free. On the other hand, a video converter is a utility program that helps you transform videos into other video or audio formats, audio to other audio formats with an aim to upscale, downscale, or even get rid of any video or audio shortcomings that prevent a smooth playback experience. This kind of software is ideal in a plethora of instances like when there is a need to cut on the cost of ownership, escape maintenance requirements, experience better quality, improve or add features to the software by adjusting the code, among other motivations that ride on the free nature of the programs. The term open source, in computing, refers to software whose source code can be adjusted, shared, and collaborated on without worrying about infringing any copyrights. ![]() ![]() ![]() Far from it, in fact! The never-ending monthly cycle of superhero material has seen the 2000s give us countless new adversaries for the likes of Spider-Man, X-Men, Fantastic Four, Daredevil and the Avengers. The Marvel character Loki has gained popularity over the years due to its popularity. However, this does not mean that Marvel writers and artists have stopped trying to create new villains. Comic book grid frame, funny oops bam smack text speech bubbles on color stripes background vector layout template Comics page. ![]() Handwriting, Calligraphy, Retro, Graffiti, and more. Akira Expanded Font Alpha Font Angry Font Marvel Font Gotham Bold Font Captain Marvel Font Glacial Indifference Font Medieval Sharp. Cartoon Comic Groovy Old School Curly Western Eroded Distorted Destroy Horror. Only a select few villains created in the 2000s have made any sort of impact at all, such as Morlun and Mister Negative. The Farmer font is a full condensed typeface with 3 unique styles: Vintage. This tool has the capacity to combine all these fonts with Retro Vintage. ![]() Hell, Red Skull even dates back to 1941, a full 20 years before the beginning of the Marvel Age of comics! More recent creations like Apocalypse, Venom and Carnage were birthed in the '80s and '90s, but after that the well-known villain pool is very shallow. Marvel is a modern and powerful typeface that is suited for branding and marketing materials, while East Broadway Font is a decorative typeface that is suited for creating a vintage or distressed aesthetic. If you look at when these villains were created, however, it's obvious that the '60s and '70s (the formative years of Marvel) were when most of the truly iconic villains reared their heads for the first time. ![]() ![]() ![]() When the upper body and arms take over, the club is thrown outside of the intended swing plane with the clubhead approaching the ball from outside to in. The origin of this dreaded out-to-in swing path usually begins in the transition from the top of the backswing to the start of the downswing, when many amateurs initiate the downswing with an overuse of the upper body and arms. ![]() Unfortunately, the majority of amateur golfers hit their drives in this manner. This right-to-left swing path, when accompanied by an open clubface, will produce a weak, left-to-right curving shot (a slice). With your focus properly on this as the root cause, you can then work on the adjustments that’ll be recommended to deliver that clubface to impact in a position that’s square to your swing path (e.g., a stronger grip, a flatter lead wrist, more forearm rotation, etc.).Īs mentioned above, there is an imaginary line that runs from just behind the ball all the way to the target (the target line).Īn out-to-in swing path is one in which the clubhead approaches the ball from outside that target line and which moves from right to left as it cuts across the ball. To learn how to fix a slice in golf, your focus first and foremost must be on the clubface. Stated simply, the reason that golfers slice the ball is because somewhere during their golf swing, they open the clubface or create the conditions for the face to be open at impact. The actual root cause of the slice is that your clubface at impact is open to your swing path. ![]() It’s a symptom of the problem or the observable result of the problem. The slice itself, while certainly problematic, isn’t the actual problem. They may talk about issues with the grip or problems with alignment or swing path, and the fixes that they recommend could very well be helpful in lessening your slice (and we’ll discuss them later in this article).īut what they usually fail to mention is the actual root cause. If you ask people who are familiar with the mechanics of the golf swing, you’ll hear several reasons cited for a slice. ![]() ![]() ![]() ![]() So Hepburn will be moving in a few months - to a Studio City low-rise. ![]() “I had a feeling the bank was going to want to take this space back and use it for its own needs. “A guy from the bank walked in back in January and said, ‘Wow, this is a tremendous office,’ ” Hepburn said. Putnam & Smith has rented the $2,700-per-month ninth floor for about a year.īut that’s about to change. Hepburn’s company represents musicians and does marketing and public relations work for nonprofit groups. The fourth and sixth floors are vacant and the 10th is used for the building’s machinery. These days the bank’s mortgage division uses the second, seventh and eighth floors, a security company rents the third and the bank’s conference room takes up the fifth floor. Several financial institutions have operated the Victory Boulevard building over the years. “Honnold designed a number of buildings that are recognized as good examples of Late Modern architecture,” including the Sunset-Vine Tower in Hollywood, a 1963 spinoff of the North Hollywood tower. “It was a little off our route, but we included it as a site of note when we did a two-day tour of Valley architectural sites in 2000,” said Ken Bernstein, director of preservation issues for the Los Angeles Conservancy. The building has long captured the imagination of Modern architecture fans. The skyscraper’s single elevator opens to 3-foot-wide “elevator lobbies” on each of the floors. Its minuscule first-floor lobby serves as an entryway not only to the tower but to an adjoining ground-floor bank office that extends outward from the building’s south side. Each floor measures a mere 1,400 square feet. Besides giving the structure extra height, the top beams are used as identifying signs.Īs soaring as it looks from the outside, the high-rise is intimate on the inside. Two thick beams at the top connect girders on the north side of the building with those on the south side. The building itself seems to be suspended between a pair of giant handles reaching nearly 12 stories in the air. He drew up the North Hollywood tower to look as if it were emerging on legs from the shopping center parking lot and storefronts beneath it. Honnold, whose other work included collaborating with Richard Neutra on downtown’s Los Angeles County Hall of Records and designing jutting-roof Tiny Naylor’s and Ship’s restaurants, knew what to do. ![]() ![]() Tuberous begonias provide more and larger flowers than most other plants that grow in shade. Tuberous Begonia - Another begonia for shade, this type has showier flowers in a greater range of colors.Flowers come in various shades of pink and orange, as well as white. Wax begonias get their name from their characteristically waxy leaves. Wax Begonia - There are many varieties of begonia that tolerate dappled shade.For bright splashes of color in shady corners, under trees, or in containers on covered patios, try these: Though its name suggests pink, coral bells’ spikes of flowers also come in white.Īnnuals may not come back year after year, but you cannot beat them for sheer flower power. Coral Bells - Also known as alumroot, this very cold hardy perennial has a low-growing, mounding habit.Primroses will bloom throughout summer and often into the fall. Primrose - These woodland natives prefer damp, shady areas that remind them of the forest floor.The striking flowers come in many colors, and most are bi-colored. Columbine - Columbine does especially well in dappled shade where summers are hot.Foamflower’s foliage is attractive too, with large, heart-shaped leaves. Foamflower - The name of this perennial perfectly describes the frothy, feathery look of the flower clusters.Some varieties of blue-eyed grass also come in white or yellow. Blue-Eyed Grass - This iris relative has long and thin, grass-like leaves with delicate flowers that are mostly blue or violet.Watch out - Japanese anemone plants spread readily. Japanese Anemone - A late-season bloomer that does fine in part shade, this will give you pretty flowers on tall thin stems in shades of pink and white.Astilbe plants come in a huge range of colors. Astilbe - Also known as false spirea, this perennial grows feathery spikes of small flowers on tall stems.The heart-shaped flowers hang from thin branches and can be deep pink or white. Bleeding Heart - This is a pretty small shrub or perennial with unique flowers.Plant them once, and they’ll come back with lovely flowers year after year. With a combination of plants that thrive in shade, do well in fall, and will look beautiful well into the winter, these planters are superstars that keep on performing with little care.All of these shade flowers are perennials and should grow and bloom well in partial or light shade. These containers were made for the shade. They do like morning sun, but in full shade they produce deeper colors-however the flowers are fewer. I pulled a few from my garden to add to these containers. In my garden they spread like crazy so I like them in containers to keep them under control. ![]() Japanese Anemone or Windflowers are a garden favorite. Plum Pudding, Berry Smoothie, and Peach Flambe are appropriately yummy descriptors for the colors gracing this fabulous foliage. Heucheras have my heart – they are so full and bright, I just want to eat them up! It doesn’t help that their names sound delicious. The lime green of the sedge complements the fiery peach Heuchera. It will produce fragrant white flowers and then red berries for a continual show throughout the year. The creeping wintergreen is an evergreen that will grow and fill in over the fall, when the leaves turn purple.
![]() These tools are often identified by their Mazda Protege 1998 1999 2000 2001 2002 2003 special tool number and illustrated. In some cases, the text refers to special tools that are recommended or required to accomplish adjustments or repairs. This includes a torque wrench to ensure that fasteners are tightened in accordance with specifications. It offers diagnostic and repair procedures to follow when trouble occurs.įor many simpler jobs, doing it yourself may be quicker than arranging an appointment to get the Mazda Protege 1998 1999 2000 2001 2002 2003 into a dealer and making the trips to leave it and pick it up.Ī lot of money can be saved by avoiding the expense the shop must pass on to you to cover its labour and overhead costs.įor those intending to do maintenance and repair on their Mazda Protege 1998 1999 2000 2001 2002 2003, it is essential that safety equipment be used and safety precautions obseved when working on the Mazda Protege 1998 1999 2000 2001 2002 2003. It provides information and procedures for routine maintenance and servicing. This manual for Mazda Protege 1998 1999 2000 2001 2002 2003 emphasizes particular information denoted by the wording and symbols: WARNING, CAUTION, NOTE. This manual includes many of the specifications and procedures that were available in an authorized Mazda Protege 1998 1999 2000 2001 2002 2003 dealer service department. The aim of this manual is to help you get the best value from your Mazda Protege 1998 1999 2000 2001 2002 2003. The manual provides the most reliable information. The purpose behind incorporating these instructions in this manual is to enable technicians to understand their functions properly and thus judge the performance of the car as a whole. For repairs of proprietary components the instructions of the respective component manufacturers are included in this manual. The manual includes instructions on components manufactured for Mazda Protege 1998 1999 2000 2001 2002 2003. This will enable you to build and maintain a reputation of quality service. The repair procedures outlined in this manual emphasize the special aspects of the product. This manual covers the repair and overhaul of Mazda Protege 1998 1999 2000 2001 2002 2003 cars and assumes that the technician is fully conversant with general automobile practices. This edition of service manual for Mazda Protege 1998 1999 2000 2001 2002 2003 was primarily published to be used by mechanical technicians who are already familiar with all service procedures relating to BRP products. ![]() ![]() So stickies has been around for 20+ years on the Mac. Join us and get exclusive content and course discounts. There you can find out more about the Patreon Campaign. MacMost is brought to you thanks to a great group of more than 700 supporters. Today let me show you all sorts of advanced tips and tricks for using stickies on your Mac. And cheers to Jens Alfke - what a legacy.Video Transcript: Hi this is Gary with. So cheers, Stickies! I’m glad you’re still around. I started with paper notebooks but, especially when working out of the home office, it was handier to have all my notes on the Mac, right beside the word processor or whatever application I was using to carry out my translations. I used to take advantage of Stickies’ flexibility especially during the first years of my career as a freelance translator, when I had to translate entire manuals, and needed to maintain a consistent technical glossary. Stickies keeps all information in a self-contained database, which can be easily backed up and migrated by copying the file StickiesDatabase, which is located in your Library ( ~/Library/StickiesDatabase). All the notes are there when you reopen it. All the notes you create are retained when quitting the app. You don’t need to use a Save command - you never needed to. More importantly, sticky notes are persistent.To save space, notes can be minimised by double-clicking on their title bars, just like you could collapse Finder windows in System 7.5 with the WindowShade feature.You can search text within a note or all the notes by pressing ⌘-F.You can (of course) choose different colours for the notes, and choose to have notes always in front of other windows or keep them semi-transparent.You can easily create bulleted/numbered lists within a note.They support formatted text, so you can write using different fonts and styles. ![]() Stickies are really versatile when you need to write down something quickly, and at the same time you want to keep notes right next to what you’re working on, exactly like their physical counterpart. The amazing thing is that, backup after backup, migration after migration, when I now launch Stickies on my iMac, I can see all the notes I’ve been retaining for the past 20 years or so. Often overlooked or dismissed, I’ve been using it on a rather constant basis probably since Mac OS 8.6 on my iMac G3 back in 1999. As you can see, the default notes have stayed the same over the years:Īs far as note taking goes, Stickies is a bit of an unsung hero among Mac applications. Here’s Stickies in OS X 10.11.6 El Capitan:Īnd here’s Stickies in Mac OS 11 Big Sur. Here’s Stickies in Mac OS X 10.5.8 Leopard (PPC): When you quit Stickies, this dialog appears. Just to show you a few examples, here’s Stickies in Mac OS 7.6.1: Stickies app icon up to Mac OS 10.15 CatalinaĪs for the app’s interface, apart from slight changes from the classic Mac OS to Mac OS X, it’s always been the same, in appearance and fundamental behaviour. It was redesigned in Big Sur to better fit its æsthetic: In Mac OS X, its icon has remained the same from version 10.0 to version 10.15. This feature was then removed with Safari 6.0 in OS X 10.8 Mountain Lion.īack to Stickies, the amazing thing about this application is that it hasn’t essentially changed for the past 27 years. After leaving the iChat project, in late 2003 he joined the Safari team and worked on what then became Safari RSS, the RSS/Atom news reader and aggregator built into Apple’s Safari, which debuted in Safari 2.0, released with Mac OS X 10.4 Tiger. He and his team later worked on expanding iChat’s features, resulting in the release of iChat AV in 2003. Later, in 2000, he started developing an instant messaging client that became iChat for Mac OS X, that was first introduced with Mac OS X 10.2 Jaguar. Between 19 he worked on the development of the OpenDoc framework. Between 19 he was part of the team that developed AppleScript he specifically helped to design the Open Scripting Architecture and created the Script Editor. Stickies was originally called Antler Notes, and in the classic Mac OS version of the app, there’s a nice Easter Egg reminding you of its origins.īy the way, during his time at Apple, Alfke contributed to many important features of the Mac operating system. ![]() He developed the application in his spare time while working at Apple. The first version of Stickies was written in 1994 by Jens Alfke, and debuted as part of System 7.5 in the same year. As I was reflecting some more about my favourite features of Mac OS X over the 20 years of its history, I realised that I needed to add a very special mention to the list - the Stickies app.Īnd as soon as I thought of Stickies, I remembered that it’s an application that’s even older than Mac OS X. ![]() ![]() ![]() Despite the fact that some may say the gameplay is shallow and monotonous. Massive scale, open-ended gameplay, and procedural creation are some of the game's most notable features. There are action and role-playing elements in SPORE, which is an online real-time strategy game. Here you can download the latest version of SPORE Full Version Torrent for free on your computer. You too can directly influence the future of your culture by creating worlds and cities. Travel, discover new universes, meet, connect or fight against other races - above all you can direct and guide evolution.Ī huge world and a lot of social media are also at your disposal. With it, other universes created by the same players will be exposed, which means that other cultures, races, and simply will not be shown. A vast universe is at your disposal, but it is not the only one. After all, your civilization could be a race for astronauts. Over time, he can evolve into an intelligent person who begins to colonize the chosen planet, build a society, and much more. But over time, that is likely to change and become an animal. But this is not the main thing! The main thing is that you have to go through five stages of development with your existence.Īt first, it will be a small embryo that cannot be seen with the naked eye. Just by creating a tiny creature, you feel power over the entire universe and love and nurture it like the doll of your eye. And yet - this simulator doesn't look like anything else right now and it's not just a tactical game, but a game with a mix of RPG elements, a sandbox, and survival. It seems that there are already many simulations of God there. SPORE Apk e is an unusual divine simulator where you can create your own unique being and eventually develop it into a real culture. In "SPORE" you can play all day and enjoy the incredible joy of changing your own life. Space, endless battles, and development in the final stages of the game. The game calculates your score at the end of each stage. ![]() These points can be obtained in different ways at different stages. Each part of the body has its own characteristics and abilities that allow you to interact or invade and subdue other species.īy mating with other members of your species, you can transform your animal. ![]() Every element of your pet, including legs, arms, and tail, can be moved or changed. You have the choice of whether your hero will be friendly and vegetarian or eat meat and fight other races. It can range from a tiny single-celled creature to an intelligent member of the space colony. SPORE Apk, You can start from scratch and create your own animal on the tracks. ![]() ![]() ![]() That day, the website was created, which features a clickable button that produces an audio clip of Petulla saying "suh dude. In the first week, the video gained over 2 million loops, 61,000 likes and 29,000 revines. On January 16th, 2016, Petulla uploaded a Vine in which he and Colletti say "suh dude" and laugh while talking on the phone (shown below). On December 28th, Petulla's retail site TrippyBurger began selling "Suh Dude" merchandise (shown below). On December 4th, Petulla uploaded a Vine in which he yells "suh dude" at a man riding a self-balancing scooter down the sidewalk (shown below). On November 22nd, Redditor guywhosaysyeah posted the video to the /r/videos subreddit. On November 20th, the Funny Things YouTube channel reuploaded the video (shown below). On November 15th, Petulla posted the mashup video to his Facebook page, where it received upwards of 8 million views and 80,000 shares over the next two months. ![]() Avocado posted the "suh dude" clips edited together. Kevlar Kid, Coo Cachoo, Royal F J, Erbeia, Fog Alert, Isle of Prado, Hot Damon, Rauschenberg, Ducane).On November 13th, 2015, Viner G. Regal Ransom, Equestrio, Awesome Gem, Giant Oak, Caracortado, Mission Impazible, Wise Dan, Demarcation). Game On Dude, Twirling Candy, Setsuko, Awesome Gem, Dark Cove, Miss Match (ARG), Soul Candy). Interactif, Codoy, Make Music for Me, Pleasant Prince, Aikenite, Odysseus). Matthew Perry, Star of ‘Friends,’ Is Dead at 54. Super Saver, Afleet Again, Ice Box, Our Dark Knight). Game On Dude, Stay Put, Interactif, Stately Victor, Ice Box, Make Music for Me, Dave in Dixie, Spangled Star, Uptowncharlybrown).Īfleet Again, A Little Warm, Friend Or Foe, Miner's Reserve, Ice Box, Trappe Shot, Super Saver, Admiral Alex). Jackson Bend, Yawanna Twist, Dublin, Paddy O'Prado, Caracortado, Super Saver, Schoolyard Dreams, Aikenite, Pleasant Prince, Northern Giant).Ī Little Warm, Exhi, Afleet Again, Severe Weather). The Director, Don Cavallo, Marching Tune, Tiz Mine, Gothics Peak, Key to the Empire, Illuminated Sky, Buzzin Ready). Information is updated daily and reflects official results as recorded by The Jockey Club Information Services records of sales outside of North America may be delayed and will appear only when recorded officially. Below the tabulated results box are listed the individual races for the subject horse with race names linked to pages with more detail about the top three finishers and an analysis provided by BloodHorse staff. Stakes performances are broken out in parentheses. Race records show the number of starts, firsts, seconds, thirds, and earnings per racing year for Northern Hemisphere racing. Services records of sales outside of North America may be delayed.įirst Dude's Complete Worldwide Auction Results Is updated daily and reflects official results as recorded by The Jockey Club Information The past two months data include results of all sales in Northern Hemisphere. ![]() Hip-by-hip sales results for the subject stallion's progeny and covered mares from More detailed searches is available at Recent Results Displays ![]() The summary results are links to worldwide hip-by-hip results for the major salesĭuring the current year and two previous years. Of North America may be delayed and will appear only when recorded officially. Results as recorded by The Jockey Club Information Services records of sales outside Information is updated daily and reflects official The current year to date and the past year data include results of all significant Summary sales results include the subject stallion's progeny and covered mares for Race data includes the race type or name (applicable to stakes), race date, race number, track, purse, distance, assigned weight, jockey, trainer, breeder and owner. For each runner is listed its post position, name, age and sex, and name of the dam. Weekly entries are published as soon as they are available through Equibase and are only for races that meet the following purse thresholds: All stakes $50,000 and up allowance races for $30,000 and up claiming and optional claiming for $50,000 and up maiden special weights for $20,000 and up and, maiden claiming races worth $20,000 or more. This section lists the progeny entered in an upcoming race in North America (U.S., Canada, and Puerto Rico) for the subject stallion. ![]() |
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